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About Nubiplant

Unique properties and nanotechnologies elements in NUBIPLANT material synthesis

Implant material is obtained by acryl-containing monomers interpolymerization

in dispersion medium excess presence, and is monolithic structure, composed of continuous cross-linked net, penetrating through the whole volume, which stability is due to Van der Waals forces, hydrogen and chemical bonds that absolutely exclude "exfoliation", "spreading", and primary components diffusion.

According to scanning electronic microscopy data, implant material

is heterogeneous system with three-dimensional structure complex hierarchy with pores sizes differing by several orders, as well as with non-porous zones with globular morphology. These pores are connected by net, forming on surface more structured barrier layer, which prevents large protein fragments penetration into implant, at the same time preserving electrolytes balance on interface that excludes fibrosis at implantation site, connective tissues elements in-growth into implant and secures foreseeable prolonged preserved effect.

Implant material has rapid relaxation. Its relaxation is connected with

mechanical properties and force application duration (deformation time). Quick relaxation after external influence excludes undesirable "plasticine" effect, which is characteristic for many implants, as well as implant presence visual signs in tissues.

Implant material has high elasticity, its relative elongation

is over 500%, and by mechanical properties it resembles India rubber, which provides for valuable in-use performance, for example, resistance to mechanical damages. It allows its implanting through small incisions, and successful application of minimally invasive implantation technologies.

Implant material contains large quantities

of physiological dispersion medium, some its modifications up to 99.5%. Water dispersion medium is necessary component for hydro-gel materials used in medical practice, in the majority of cases exactly for their biological properties manifestation. Water state and content in hydro-gels has decisive effect on diffusion into them of organic and non-organic substances. Liquid molecules diffusion in hydro-gel is described by effective medium model, and happens by hydro-dynamic interaction mechanism with polymeric net. Through polymeric net density variability we implemented ideal "free" to "bounded" water ration, which allowed to regulate sorption and desorption of different substances maintaining Donnan equilibrium at interface of phases.

Implant material has high cohesiveness (internal cohesion forces

prevail over external adhesion forces), it ensures material form-stability and excludes connective tissue elements in-growth into implant, provides for foreseeable prolonged preserving effect, and significantly decreases complication incidence.






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